WWII Wound Tablets \"UPJOHN CO.\" (8 Sulfadiazine), 1st Aid Kits, Jungle M-2 for Sale

WWII Wound Tablets \"UPJOHN CO.\" (8 Sulfadiazine), 1st Aid Kits, Jungle M-2 For Sale

$WWII Wound Tablets \$
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WWII Wound Tablets \"UPJOHN CO.\" (8 Sulfadiazine), 1st Aid Kits, Jungle M-2:
$215.00

WWII Wound Tablets \"UPJOHN CO.\" (8 Sulfadiazine), 1st Aid Kits, Jungle M-2
ORIGINAL wartime issue item!!!
SCARCE! SCARCE!This is an intact, undamaged tan paper-foil laminate package with the plastic tray with the sliding cover on the inside. The raised lettering on the top of the plastic tray, UPJOHN is clearly visible beneath the foil-laminate. TAN paper foil-laminate, folded in half, hermetically sealed, with printing in RED and BLACK end borders.+ This example is in EXCELLENT+++ condition!!+ These Sulfadiazine Tablets were included in numerous first aid kits (e.g. the Parachutist\'s First Kit worn by pilots, aviators, paratroopers, the Aeronautic First Aid Kit, the Individual Jungle First Aid Roll, the M2 Jungle First Aid Kit, as well as in the Satchels of USMC Corpsmen and Army Medics.Front (obverse):
SULFADIAZINE TABLETS, U.S.P.7.7 GRS. (0.5 GM.) EACHUSE: TO BE TAKEN IN CASE OF
A SEVERE WOUNDSee the reverse side for directionsTHE UPJOHN COMPANYKALAMAZOO, MICH.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
TO OPEN TEAR ALONG DOTED LINE
Back (reverse):
DIRECTIONS:TAKE BY MOUTH FOLLOWEDBY A LARGE AMOUNT OF WATER,
8 SULFADIAZINE TABLETS
CAUTION: DO NOT TAKE ANY OF THESETABLETS UNLESS LARGE AMOUNTS OFWATER CAN BE TAKEN BOTH WITH THETABLETS AND FOR 24 HOURS AFTERWARDSTHE UPJOHN COMPANYKALAMAZOO, MICH.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
TO OPEN TEAR ALONG DOTED LINE*****The Upjohn Companywas an American pharmaceutical manufacturing firm founded in 1886 in Hastings, Michigan by Dr. William E. Upjohnn who was an 1875 graduate of the University of Michigan medical school. The company was originally formed to makefriable pills, which were specifically designed to be easily digested. They could be \"reduced to a powder under the thumb\", a strong marketing argument at the time.*****Background information from the excellent WWII MEDICAL RESEARCH CENTRE:

In 1942, in addition to their 5 grams of Crystalline Sulfanilamide, individual troops were also issued with 8 Tablets of Sulfadiazine (packed separately, and not included in the metal or plastic individual first aid packet). When wounded, unless in the abdomen or throat, troops were instructed to take 4 grams of Sulfadiazine orally, which amounted to 8 Tablets, with a large amount of water. The administration of Sulfadiazine would continue until surgery was initiated (where necessary). The Army prescribed the following dosages for Sulfadiazine Tablets:

Initial Dosage: 2 to 4 grams
Maintenance Dosage: 1 gram every 4 to 6 hours, until the drug is discontinued

Sulfadiazine is a sulfonamide antibiotic. It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections. This drug was one of the least toxic ones, and indeed the most useful of all Sulfonamides. Its use for treatment of various injuries was however discontinued after the war, becoming dependent upon the discretion of the treating medical Officer.

Sulfadiazine tablets were supplied in small, plastic containers, ordinarily each containing 8 Tablets (4 grams). Unlike Crystalline Sulfanilamide, the practice of administrating Sulfadiazine continued long into the war, and indeed limited supplies of Sulfadiazine meant that Prisoners of War received only Sulfadiazine Tablets as a means of treating minor or mild wounds.

It must be noted that liberal use of Sulfa Drugs and Penicillin in WW2 kept the incidence of serious wound infection low, in spite of surgical backlog, and the fact that many casualties occurred on pastures and farmland contaminated with animal and human feces.

Remark:
Other products of the Sulfonamide family were Sulfamerizine, Sulfaguanidine, Sulfapyridine, and Sulfathiazole.

Caution:

Almost every packet of Sulfadiazine Tablets supplied to the United States Army indicated that the contents should not be administered if the casualty was hit in the stomach. This warning was issued due to the drug’s ability to cause a sense of nausea and abdominal cramps, and administering the drug in these situations could only further enhance these side effects. Apart from this it was later found that necessary precaution was to be taken when employing compounds of the Sulfonamide group, because of a possible sensitivity of the patient, resulting in toxic reactions to the kind of drug administered.